The research in the Molecular Biophysics lab ranges from molecular to systems size levels. In particular, we study the structure and mechanics of viral capsids, their interaction with host cell molecules and the mechanisms of nanoparticle self-assembly. Viral assembly and genome-capsid interactions are closely related and for many viruses assembly is crucially dependent on the encapsulated cargo. We study this assembly and the related cargo-capsid interactions with various biophysical techniques, including (high-speed) atomic force microscopy, optical tweezers and fluorescence microscopy.