We are interested in the structure, function, and engineering of protein compartments, protein organelles, protein machines, and enzyme filaments. The systems we work on are involved in various aspects of microbial metabolism, including detoxification, stress resistance, nutrient utilization, and natural product biosynthesis. Our engineering and synthetic biology work is focused on nanocarriers for therapeutics delivery, enzyme nanoreactors for biocatalysis, and nanotechnological tool development for basic science applications.